毛东海

姓 名:毛东海 性 别:男

职 务:

职 称:研究员 学 历:博士

电 话:0731-84619748 通迅地址:湖南省长沙市芙蓉区远大二路644号

传 真:(86)-731-84612685 邮政编码:410125

电子邮件:donghai.mao@isa.ac.cn

简历

1982年出生,湖南永州人。博士,研究员,硕士生导师,中心副主任,中国科学院青年创新促进会会员。2004年在华中农业大学植物科学技术学院获农学本科学位;2010年在华中农业大学生命科学技术学院暨作物遗传改良国家重点实验室获理学博士学位;随后进入中国科学院亚热带农业生态研究所工作至今,先后任助研、副研、研究员。目前主要从事水稻高产与耐逆(低温与高温等)的遗传基础及其驱动水稻生态型形成的进化机制研究,涉及数量遗传学、分子遗传学、表观遗传学、生物化学与分子设计育种等方面。目前已在Proc Natl Acad Sci USA、Theor Appl Genet、Plant Sci、BMC Genomics、BMC Plant Biol、Mol Breed等期刊上发表论文20余篇,申请国家专利4项。主要代表成果包括:(1)发掘水稻耐冷QTL-HAN1等,并解析温带粳稻形成的部分遗传机制(PNAS,2019);(2)系统剖析高纬度分布的野生稻低温适应性的遗传机制(TAG,2015;MB,2019)。(3)解析水稻绿色革命后的高产遗传基础(PNAS,2016;MB,2020)。

承担科研项目

1.国家自然科学基金面上项目:水稻苗期耐冷基因HAN2的克隆与功能机理分析,2021-2024,58万,项目主持

2.国家自然科学基金面上项目:水稻苗期耐冷基因qCTS11的克隆与功能分析,2014-2017,87万,项目主持

3.国家自然科学基金青年项目:东乡野生稻越冬耐寒性的遗传分析,2012-2014,23万,项目主持

4.中国科学院青年创新促进会项目:茉莉酸对水稻耐冷性的分子调控机制,2018-2021,80万,项目主持

5.湖南省重点研发计划国际合作项目:水稻淹涝适应性的遗传基础及其栽培轻简化应用,2020-2022,50万,项目主持

6.湖南省自然科学基金创新群体:稻田生态系统提质增效与生态功能协调机制,2019-2021,100万,科研骨干

7.亚热带所青年人才领域前沿项目:水稻亚种间耐冷性差异的转录组分析,2012-2015,20万,项目主持

代表论著

Li X, Xiang FJ, Zhang W, Yan J, Li X, Zhong M, Yang P, Chen CY, Liu XM, Mao DH, Zhao XY (2021) Characterization and fine mapping of a new dwarf mutant in Brassica napus. BMC Plant Biol. 21(1):117. (Corresponding author)

Yu YL, Hu XJ, Zhu YX, Mao DH (2020) Re-evaluation of the rice ‘Green Revolution’ gene: the weak allele SD1-EQ from japonica rice may be beneficial for super indica rice breeding in the post-Green Revolution era. Mol Breed. 40:84. (Corresponding author)

Mao DH, Xin YY, Tan YJ, Hu XJ, Bai JJ, Liu ZY, Yu YL, Li LY, Peng C, Fan T, Zhu YX, Guo YL, Wang S, Lu DP, Xing YZ, Yuan LP, Chen CY(2019) Natural variation in the HAN1 gene confers chilling tolerance in rice and allowed adaptation to a temperate climate. Proc Natl Acad Sci USA. 113(41): 116(9):3494-3501.

Li LY, Chen HP, Mao DH (2019) Pyramiding of rapid germination loci from Oryza Sativa cultivar ‘Xeqingzao B’ and cold tolerance loci from Dongxiang wild rice to increase climate resilience of cultivated rice. Mol breed. 39:85. (Corresponding author)

Li LY, Mao DH (2018) Deployment of cold tolerance loci from Oryza sativa ssp. Japonica cv. ‘Nipponbare’ in a high-yielding Indica rice cultivar 93-11. Plant breed. 137(4) 553-560. (Corresponding author)

Li DY, Huang ZY, Song SH, Xin YY, Mao DH, Lv QM, Zhou M, Tian DM, Tang MF, Wu Q, Liu X, Chen TT, Song XW, Fu XQ, Zhao BR, Liang CZ, Li AH, Liu GZ, Li SG, Hu SN, Cao XF, Yu J, Yuan LP, Chen CY, Zhu LH (2016) Integrated analysis of phenome, genome, and transcriptome of hybrid rice uncovered multiple heterosis-related loci for yield increase. Proc Natl Acad Sci USA. 113(41):E6026-E6035. (Co-first author)

Mao DH, Yu L, Chen DZ, Li LY, Zhu YX, Xiao YQ, Zhang DC, Chen CY (2015) Multiple cold resistance loci confer the high cold tolerance adaptation of Dongxiang wild rice (Oryza rufipogon) to its high-latitude habitat. Theor Appl Genet. 128(7):1359-71.

Zhang L, Mao DH, Xing F, Bai XF, Zhao H, Yao W, Li G, Xie WB, Xing YZ (2015) Loss of function of OsMADS3 via the insertion of a novel retrotransposon leads to recessive male sterility in rice (Oryza sativa). Plant Sci. 238:188-97. (Co-first author)

Tang M, Mao DH, Xu LW, Li DY, Song SH, Chen CY (2014) Integrated analysis of miRNA and mRNA expression profiles in response to Cd exposure in rice seedlings. BMC Genomics. 15:835. (Co-first author)

Mao DH, Chen CY (2012) Colinearity and similar expression pattern of rice DREB1s reveal their functional conservation in the cold-responsive pathway. PLoS One. 7(10):e47275.

Mao DH, Yu HH, Liu TM, Yang GY, Xing YZ (2011) Two complementary recessive genes in duplicated segments control etiolation in rice. Theor Appl Genet. 122(2):373-83.

Mao DH, Liu TM, Xu CG, Li XH, Xing YZ (2011) Epistasis and complementary gene action adequately account for the genetic bases of transgressive segregation of kilo grain weight in rice. Euphytica. 180(2):261-271.

Li GW, Jin JY, Zhou Y, Bai XF, Mao DH, Tan C, Wang GW, Ouyang YD (2019). Genome-wide dissection of segregation distortion using multiple inter-subspecific crosses in rice. Science China Life Sciences. 62: 507.

Tang M, Zhou CS, Meng L, Mao DH, Peng C, Zhu YX, Huang DY, Tan ZL, Chen CY, Liu CB, Zhang DC (2016) Overexpression of OsSPL9 enhances accumulation of Cu in rice grain and improves its digestibility and metabolism. J Genet Genomics. 43(11):673-676.

Bai XF, Huang Y, Mao DH, Wen M, Zhang L, Xing YZ (2016) Regulatory role of FZP in the determination of panicle branching and spikelet formation in rice. Sci Rep. 6:19022.

Wu B, Mao DH, Liu TM, Li ZX, Xing YZ (2015) Two quantitative trait loci for grain yield and plant height on chromosome 3 are tightly linked in coupling phase in rice. Mol Breeding. 35: 156.

Yao WY, Sun L, Zhou H, Yang F, Mao DH, Wang JR, Chen LH, Zhang GY, Dai JP, Xiao GY, Chen C (2015) Additive, dominant parental effects control the inheritance of grain cadmium accumulation in hybrid rice. Mol Breeding. 35: 39.

Yang CH, Li DY, Mao DH, Liu X, Ji CJ, Li XB, Zhao XF, Cheng ZK, Chen CY, Zhu LH (2014) Overexpression of microRNA319 impacts leaf morphogenesis and leads to enhanced cold tolerance in rice (Oryza sativa L.). Plant Cell Environ. 36(12):2207-18.

Liu TM, Mao DH, Zhang SP, Xu CG, Xing YZ (2009) Fine mapping SPP1, a QTL controlling the number of spikelets per panicle, to a BAC clone in rice (Oryza sativa). Theor Appl Genet. 118(8):1509-17.

Liu TM, Mao DH, Bai XF, Xu CG, Zhang QF, Xing YZ (2007) Comparison of QTL for grain number per panicle in three populations sharing 3 parents and fine mapping of Gn1c. Molecular Plant Breeding. 5: 221-222.

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